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Bioinformatics

Bioinformatics is a subfield of Computational Biology (along with Systems Biology, Molecular Dynamics, and Ecological Modeling), and is focused on the storage, access, and analysis of the vast amount of biological data now available.

For biologists, the ability to use bioinformatic tools for data retrival and analysis has become an essential and routine activity, similar to the use of word processors or spreadsheet programs.

Our workshop will expose you to several bioinformatic applications, and you will generally use these tools to analyze the data you obtain in the laboratory. You will also become familiar with how to set up meaningful activities to teach these skills in the classroom.

 

Contents

  1. Integrated Student Project using the NCBI database and ClustalW to answer taxonomic questions using phylogenetic trees. (PDF) (PPT) (HTML) (DOC)
  2. Use of Chromas to read data from a sequencing machine.
    (PDF) (PPT) (HTML) (DOC)
  3. Use of an ASCII editor to prepare sequence files.
    (PDF) (PPT) (HTML) (DOC)
  4. Use of ORF Finder to identify protein-coding regions.
    (PDF) (PPT) (HTML) (DOC)
  5. Use of BLAST to compare sequence to database.
    (PDF) (PPT) (HTML) (DOC)
  6. Use of Clustal to prepare multiple sequence alignments.
    (PDF) (PPT) (HTML) (DOC)
  7. Using Cn3D to view protein structures in three dimensions.
    (PDF) (PPT) (HTML) (DOC)
  8. Hands-on Primer-matching Activity
    (PDF) (PPT) (HTML) (DOC)
  9. Working with ITS and planning restriction digests virtually.
    (PDF) (PPT) (HTML) (DOC)
  10. Bioinformatics Careers
    (PDF) (PPT) (HTML) (DOC)
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